Institute of Food, Nutrition and Health, ETH Zurich, 8092 Zurich, Switzerland.
University of California, 510 Barker Hall, Berkeley, CA 94720, USA.
Viruses. 2010 Apr;2(4):961-971. doi: 10.3390/v2040961. Epub 2010 Apr 6.
Three different Bacillus bacteriophages designated TP21 are known from the literature. We have determined the sequence and structure of the TP21-L genome, and compared it to the other phages. The genome is 37.5 kb in size, possesses fixed invariable genome ends and features the typical modular organization of a temperate siphovirus. TP21-L is neither identical to TP21 isolated by Thorne (TP21-T), as shown by a PCR-based approach nor to TP21 isolated by He et al. (TP21-H), as estimated from phage dimensions. For reasons of clarity, we suggest renaming the different TP21 isolates.
文献中已知有三种不同的芽孢杆菌噬菌体,分别编号为 TP21。我们已经确定了 TP21-L 基因组的序列和结构,并将其与其他噬菌体进行了比较。该基因组大小为 37.5kb,具有固定不变的基因组末端,并且具有温和的长尾噬菌体的典型模块化组织。如基于 PCR 的方法所示,TP21-L 与 Thorne 分离的 TP21(TP21-T)并不相同,也与 He 等人分离的 TP21(TP21-H)不同,从噬菌体尺寸估计。为了清晰起见,我们建议重新命名不同的 TP21 分离株。