完整的核苷酸序列和分子特征的芽孢杆菌噬菌体 TP21 及其与其他同名噬菌体的亲缘关系。
Complete Nucleotide Sequence and Molecular Characterization of Bacillus Phage TP21 and its Relatedness to Other Phages with the Same Name.
机构信息
Institute of Food, Nutrition and Health, ETH Zurich, 8092 Zurich, Switzerland.
University of California, 510 Barker Hall, Berkeley, CA 94720, USA.
出版信息
Viruses. 2010 Apr;2(4):961-971. doi: 10.3390/v2040961. Epub 2010 Apr 6.
Three different Bacillus bacteriophages designated TP21 are known from the literature. We have determined the sequence and structure of the TP21-L genome, and compared it to the other phages. The genome is 37.5 kb in size, possesses fixed invariable genome ends and features the typical modular organization of a temperate siphovirus. TP21-L is neither identical to TP21 isolated by Thorne (TP21-T), as shown by a PCR-based approach nor to TP21 isolated by He et al. (TP21-H), as estimated from phage dimensions. For reasons of clarity, we suggest renaming the different TP21 isolates.
文献中已知有三种不同的芽孢杆菌噬菌体，分别编号为 TP21。我们已经确定了 TP21-L 基因组的序列和结构，并将其与其他噬菌体进行了比较。该基因组大小为 37.5kb，具有固定不变的基因组末端，并且具有温和的长尾噬菌体的典型模块化组织。如基于 PCR 的方法所示，TP21-L 与 Thorne 分离的 TP21（TP21-T）并不相同，也与 He 等人分离的 TP21（TP21-H）不同，从噬菌体尺寸估计。为了清晰起见，我们建议重新命名不同的 TP21 分离株。
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