Li Gang, Nie Jingxin, Shen Dinggang
Department of Radiology and BRIC, University of North Carolina at Chapel Hill, USA.
Med Image Comput Comput Assist Interv. 2011;14(Pt 2):671-9. doi: 10.1007/978-3-642-23629-7_82.
Accurate and consistent reconstruction of cortical surfaces from longitudinal human brain MR images is of great importance in studying subtle morphological changes of the cerebral cortex. This paper presents a new deformable surface method for consistent and accurate reconstruction of inner, central and outer cortical surfaces from longitudinal MR images. Specifically, the cortical surfaces of the group-mean image of all aligned longitudinal images of the same subject are first reconstructed by a deformable surface method driven by a force derived from the Laplace's equation. And then the longitudinal cortical surfaces are consistently reconstructed by jointly deforming the cortical surfaces from the group-mean image to all longitudinal images. The proposed method has been successfully applied to both simulated and real longitudinal images, demonstrating its validity.
从纵向人脑磁共振图像中准确且一致地重建皮质表面,对于研究大脑皮质的细微形态变化具有重要意义。本文提出了一种新的可变形表面方法,用于从纵向磁共振图像中一致且准确地重建内、中、外皮质表面。具体而言,首先通过由拉普拉斯方程导出的力驱动的可变形表面方法,重建同一受试者所有对齐纵向图像的组均值图像的皮质表面。然后,通过将组均值图像的皮质表面共同变形到所有纵向图像,一致地重建纵向皮质表面。所提出的方法已成功应用于模拟和真实的纵向图像,证明了其有效性。