先天性皮肤发育不全及孕期暴露于甲巯咪唑相关的其他异常情况。
Aplasia cutis congenita and other anomalies associated with methimazole exposure during pregnancy.
作者信息
Rodríguez-García Cristina, González-Hernández Sorahaya, Hernández-Martín Angela, Pérez-Robayna Nuria, Sánchez Rosalba, Torrelo Antonio
机构信息
Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna (Canary Islands), Spain.
Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
出版信息
Pediatr Dermatol. 2011 Nov-Dec;28(6):743-745. doi: 10.1111/j.1525-1470.2011.01572.x. Epub 2011 Oct 13.
Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy.
先天性皮肤发育不全（ACC）是一种先天性缺陷，表现为局限性皮肤缺失，通常累及头皮。其病因尚不确定，已有多种致畸剂如甲巯咪唑与之相关。我们报告了两例孕期暴露于甲巯咪唑的新生儿发生ACC及其他异常的病例。
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