Department of Epidemiology, School of Public Health, Aarhus University, Denmark.
Alcohol Clin Exp Res. 2012 May;36(5):807-14. doi: 10.1111/j.1530-0277.2011.01657.x. Epub 2011 Oct 13.
To examine the effects of low to moderate alcohol consumption during pregnancy on child motor function at age 5.
A prospective follow-up study of 685 women and their children sampled from the Danish National Birth Cohort based on maternal alcohol consumption during pregnancy. At 5 years of age, the children were tested with the "Movement Assessment Battery for Children" (MABC). Parental education, maternal IQ, prenatal maternal smoking, the child's age at testing, and gender of child were considered core confounders, while the full model also controlled for prenatal maternal binge drinking episodes, age, maternal prepregnancy body mass index, parity, home environment, postnatal parental smoking, health status, and indicators for hearing and vision impairment.
There were no systematic or significant differences in motor function between children of mothers reporting low to moderate levels of average alcohol consumption during pregnancy and children of mothers who abstained.
In this study, we found no systematic association between low to moderate maternal alcohol intake during pregnancy and child motor function at age 5.
研究孕期低至中度饮酒对 5 岁儿童运动功能的影响。
对丹麦全国出生队列中 685 名女性及其子女进行前瞻性随访研究，依据孕期母亲饮酒情况进行抽样。在 5 岁时，对儿童进行“儿童运动评估电池”（MABC）测试。父母教育程度、母亲智商、孕期母亲吸烟、儿童测试年龄和性别被认为是核心混杂因素，而全模型还控制了孕期母亲 binge drinking 发作、年龄、母亲孕前体重指数、产次、家庭环境、产后父母吸烟、健康状况以及听力和视力障碍指标。
报告孕期低至中度平均饮酒量的母亲所生孩子与不饮酒母亲所生孩子的运动功能之间没有系统或显著差异。
在这项研究中，我们没有发现孕期低至中度母亲饮酒与 5 岁儿童运动功能之间存在系统关联。
