亨特综合征：使用艾杜糖醛酸硫酸酯酶进行9个月酶替代治疗后广泛典型皮肤病变的消退
Hunter syndrome: resolution of extensive typical skin lesions after 9 months of enzyme replacement therapy with idursulfase.
作者信息
Marín Laura L, Gutiérrez-Solana Luis G, Fernández Antonio T
机构信息
Department of Neurology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
出版信息
Pediatr Dermatol. 2012 May-Jun;29(3):369-70. doi: 10.1111/j.1525-1470.2011.01418.x. Epub 2011 Oct 13.
Abstract
A 10-year-old boy with Hunter syndrome and extensive typical skin lesions underwent 9 months of enzyme replacement therapy, after which the skin lesions disappeared. We believe that treatment with idursulfase probably removes the cutaneous storage of glucosaminoglycans in Hunter syndrome.
摘要
一名患有亨特综合征且有广泛典型皮肤病变的10岁男孩接受了9个月的酶替代疗法，之后皮肤病变消失。我们认为，用艾度硫酸酯酶治疗可能消除了亨特综合征中葡糖胺聚糖的皮肤蓄积。
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