Department of Ophthalmology, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Am J Ophthalmol. 2012 Mar;153(3):560-3. doi: 10.1016/j.ajo.2011.08.019. Epub 2011 Oct 13.
To evaluate the long-term results of medial rectus recessions augmented by botulinum toxin injection for treating infants with large-angle (> 60 prism diopters [PD]) infantile esotropia.
Interventional case series.
Hospital-based clinical practice.
Twenty-three patients with large-angle infantile esotropia who were followed for at least 2 years postoperatively.
Surgical treatment with botulinum toxin in addition to bilateral medial rectus muscle recessions. The preoperative findings, treatment, and outcomes were reviewed.
Surgery was considered successful if the patients did not require additional horizontal strabismus surgery and had less than 10 PD of horizontal deviation.
The age at surgery ranged from 4 to 36 months (mean 14.5 months) and the angle of esotropia ranged from 65 to 100 PD (mean 72 PD). Treatment was successful in 17 of 23 patients (74%), with follow-up of 2 to 13 years (mean 6.6 years).
Botulinum toxin-augmented medial rectus recession is an effective treatment for large-angle infantile esotropia, with stable results over time.
评估肉毒毒素注射增强内直肌后退术治疗大角度 (> 60 棱镜屈光度 [PD]) 婴儿内斜视的长期疗效。
介入性病例系列研究。
医院临床实践。
23 例大角度婴儿内斜视患者，术后至少随访 2 年。
肉毒毒素联合双侧内直肌后退术的手术治疗。回顾术前发现、治疗和结果。
如果患者不需要额外的水平斜视手术，且水平斜视度小于 10 PD，则认为手术成功。
手术年龄为 4 至 36 个月（平均 14.5 个月），斜视角度为 65 至 100 PD（平均 72 PD）。23 例患者中 17 例（74%）治疗成功，随访 2 至 13 年（平均 6.6 年）。
肉毒毒素增强内直肌后退术是治疗大角度婴儿内斜视的有效方法，随着时间的推移，疗效稳定。
