干细胞：保持 BMP 信号局部化。

Stem cells: keeping BMP signaling local.

机构信息

Stowers Institute for Medical Research, Kansas City, MO 64110, USA.

出版信息

Curr Biol. 2011 Oct 11;21(19):R809-11. doi: 10.1016/j.cub.2011.08.051.

DOI:10.1016/j.cub.2011.08.051

PMID:21996502

Abstract

In stem cell niches, the spatial extent of growth factor signaling needs to be tightly controlled. A new study on the Drosophila testicular germline stem cell niche has revealed that BMP signaling is locally activated through linkage to adherens junctions.

摘要

在干细胞龛中，生长因子信号的空间范围需要被严格控制。一项关于果蝇生殖干细胞龛的新研究表明，BMP 信号通过与黏着连接的连接而被局部激活。