突触带：启动囊泡释放的机器？

Synaptic ribbons: machines for priming vesicle release?

机构信息

MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.

出版信息

Curr Biol. 2011 Oct 11;21(19):R819-21. doi: 10.1016/j.cub.2011.08.038.

DOI:10.1016/j.cub.2011.08.038

PMID:21996507

Abstract

Synaptic ribbons are specialized organelles that hold vesicles close to the active zone of sensory synapses, but their function is mysterious. Acute disruption of the ribbon complex using light has now revealed that it has a role in priming synaptic vesicles for fusion.

摘要

突触棘是一种特化的细胞器，它将囊泡保持在感觉突触的活性区附近，但它的功能是神秘的。现在，使用光来急性破坏带状复合物表明，它在启动突触囊泡融合方面发挥了作用。