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挤压创伤患者的主动脉损伤:不同的机制,不同的处理方法。

Aortic injuries in crush trauma patients: different mechanism, different management.

机构信息

Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coruña, Spain.

出版信息

Injury. 2013 Jan;44(1):60-5. doi: 10.1016/j.injury.2011.09.022. Epub 2011 Oct 11.

DOI:10.1016/j.injury.2011.09.022
PMID:21996562
Abstract

BACKGROUND

The objective of this study is to report the clinical and radiological characteristics and early and long-term survival of a series of acute traumatic aortic injuries (ATAI) in crush trauma patients, and to compare such data with our last 30 years experience managing ATAI in deceleration non-crush trauma patients.

METHODS

From January 1980 to December 2010, 5 consecutive ATAI in crush trauma and 69 in non-crush trauma patients were admitted at our institution. ISS, RTS and TRISS scores were similar in both groups.

RESULTS

Overall in-hospital mortality was 24.3%. There was no in-hospital mortality in crush patients and 26.1% in non-crush patients (p=0.32). All aortic-related complications occurred in non-crush patients. Median follow-up was 129 months (range 3-350 months). Non-crush group survival was 76.8% at 1 year, 73.6% at 5 years, and 71.2%% at 10 years. There was no mortality during follow-up in the crush group. Mean (SD) peak creatine phosphokinase was significantly higher in crush group than in non-crush group: 7598 (3690) IU/L vs. 3645 (2506) IU/L; p=0.041. Incidence of acute renal injury was higher in crush trauma patients (100% vs. 36.2%; p=0.018). Low-severity injuries were more common in crush trauma patients (100% in crush patients vs. 43.5% in non-crush patients, p=0.04).

CONCLUSIONS

Aortic injuries in crush thoracic trauma patients seem to present in a different clinical scenario from aortic injuries in high-speed thoracic trauma thus requiring distinct considerations. When planning the initial management of aortic injuries in crush trauma, the increased risk of rhabdomiolysis and subsequent acute renal failure, as well as a tendency to develop lower-risk aortic wall injuries, must be considered.

摘要

背景

本研究旨在报告一系列创伤性主动脉损伤(ATAI)的临床和影像学特征及早期和长期生存情况,并与过去 30 年减速非创伤性 ATAI 患者的治疗经验进行比较。

方法

1980 年 1 月至 2010 年 12 月,连续收治 5 例创伤性挤压综合征患者的 ATAI 和 69 例减速非创伤性 ATAI 患者。ISS、RTS 和 TRISS 评分在两组间相似。

结果

总体院内死亡率为 24.3%。挤压组无院内死亡,非挤压组为 26.1%(p=0.32)。所有主动脉相关并发症均发生在非挤压组。中位随访时间为 129 个月(3-350 个月)。非挤压组 1 年生存率为 76.8%,5 年生存率为 73.6%,10 年生存率为 71.2%。挤压组随访期间无死亡。挤压组的肌酸磷酸激酶峰值(3690IU/L)显著高于非挤压组(7598IU/L)(p=0.041)。挤压组急性肾损伤发生率较高(100% vs. 36.2%,p=0.018)。挤压组多为轻度损伤(100% vs. 43.5%,p=0.04)。

结论

与高速胸外伤所致的主动脉损伤相比,挤压胸外伤患者的主动脉损伤似乎表现出不同的临床特征,因此需要进行不同的考虑。在计划挤压性胸外伤的主动脉损伤初始治疗时,必须考虑横纹肌溶解症和随后的急性肾衰竭风险增加,以及更倾向于发展为低风险主动脉壁损伤的情况。

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