Katayama Y, Yoneda K, Kawada Y, Moriwaki K, Matsuyama T, Urata T
Division of Clinical Laboratory, National Cardiovascular Center, Hospital, Suita.
Rinsho Byori. 1990 May;38(5):553-8.
Measurement of serum myoglobin, CK-MM isoforms and CK-MB isoenzyme protein are useful for diagnosis and therapy of acute myocardial infarction (AMI). As latex agglutination turbidimetry of serum myoglobin is an easy and rapid assay method, it can be applied for early diagnosis of AMI and its observation of progress after break out of AMI. CK-MM isoforms also can be applicable for early diagnosis of AMI. The assay method of CK-MB isoenzyme protein by immunochemiluminescence is useful for anticipating the infarct size of AMI since this format is not influenced by CK-BB, myokinase, or mitochondria CK.
血清肌红蛋白、肌酸激酶-MM同工酶及肌酸激酶-MB同工酶蛋白的检测对急性心肌梗死(AMI)的诊断和治疗具有重要意义。由于血清肌红蛋白的乳胶凝集比浊法是一种简便快速的检测方法,可用于AMI的早期诊断及其发作后的病情观察。CK-MM同工酶也可用于AMI的早期诊断。免疫化学发光法检测CK-MB同工酶蛋白有助于预测AMI的梗死面积,因为这种检测形式不受CK-BB、肌激酶或线粒体CK的影响。