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中国妊娠的药物流产与手术流产方法:成本最小化分析。

Medical versus surgical abortion methods for pregnancy in China: a cost-minimization analysis.

机构信息

Department of Obstetrics and Gynecology, First Municipal Hospital of Guangzhou, Affiliated to Guangzhou Medical College, Guangzhou, China.

出版信息

Gynecol Obstet Invest. 2011;72(4):257-63. doi: 10.1159/000328313. Epub 2011 Oct 13.

Abstract

BACKGROUND

Both medical and surgical abortions are popular in developing countries. However, the monetary costs of these two methods have not been compared.

METHODS

430 women seeking abortions were recruited in 2008. Either a medical or surgical method was used for the abortion. We adopted the perspective of a third-party payer. Cost-minimization analysis was used based on all charges for the overall procedures in an out-patient clinic in Guangzhou, China.

RESULTS

219 subjects (51%) chose a medical method (mifepristone and misoprostol), whereas 211 subjects (49%) chose a surgical method. The efficacy in the surgical group was significantly higher than in the medical group (100 vs. 90%, p < 0.001). Surgical abortion incurred much more costs than medical abortion on average after initial treatment. When the subsequent costs were accumulated within the 2-week follow-up, the mean total cost in the medical group increased significantly due to failure of abortion and persistent bleeding. Patients undergoing medical abortion eventually incurred equivalent expenses compared to patients undergoing surgical abortion (p = 0.42).

CONCLUSIONS

There was no difference in the mean final costs between the two abortion methods. Complications of persistent bleeding and failure to abort (requiring surgical intervention) in the medical treatment group increased the final mean total cost substantially.

摘要

背景

在发展中国家,药物流产和手术流产都很常见。然而,这两种方法的费用尚未进行比较。

方法

2008 年招募了 430 名寻求堕胎的女性。这些女性可以选择药物流产或手术流产。我们采用第三方付费者的观点。基于中国广州一家门诊的所有费用,采用成本最小化分析。

结果

219 名受试者(51%)选择药物流产(米非司酮和米索前列醇),211 名受试者(49%)选择手术流产。手术组的疗效明显高于药物组(100%比 90%,p < 0.001)。初次治疗后,手术流产的平均费用明显高于药物流产。在 2 周随访期间,药物流产组因流产失败和持续出血而导致后续费用累计,其平均总费用显著增加。药物流产组的最终费用与手术流产组相当(p = 0.42)。

结论

两种流产方法的最终平均费用无差异。药物流产组持续出血和流产失败(需要手术干预)的并发症显著增加了最终的平均总费用。

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