Department of Medicine, The Methodist Hospital, Weill Cornell Medical College, Houston, TX 77030, USA.
J Gastrointest Surg. 2011 Dec;15(12):2262-6. doi: 10.1007/s11605-011-1718-0. Epub 2011 Oct 15.
Acquired angioedema (AAE), an acquired deficiency of C1esterase inhibitor, is a medically treatable condition which can cause severe abdominal pain mimicking an acute surgical abdomen. This disorder is strongly associated with chronic lymphocytic leukemia (CLL) and other indolent lymphoplasmacytic disorders.
We describe a patient with known CLL who developed incapacitating, recurrent severe abdominal pains, culminating in partial bowel resection. Signs, symptoms, laboratory and pathologic findings demonstrated AAE.
Wider appreciation of the possibility of AAE, particularly in patients with lymphoproliferative disorders, could lead to preventive therapy and spare unnecessary surgery. This is more important now that more effective medical therapies are available.
获得性血管性水肿（AAE）是一种获得性 C1 酯酶抑制剂缺乏症，可引起类似急性外科腹痛的严重腹痛，需要进行医学治疗。这种疾病与慢性淋巴细胞白血病（CLL）和其他惰性淋巴浆细胞疾病密切相关。
我们描述了一位已知患有 CLL 的患者，他出现了使人虚弱的、反复发作的严重腹痛，最终导致部分肠切除术。体征、症状、实验室和病理发现均表明存在 AAE。
更广泛地认识到 AAE 的可能性，特别是在淋巴增生性疾病患者中，可以进行预防性治疗，避免不必要的手术。现在有了更有效的医学治疗方法，这一点更加重要。
