Dermatologic Department, San Paolo Hospital, University of Milan, Milan, Italy.
Mycopathologia. 2012 Mar;173(2-3):135-8. doi: 10.1007/s11046-011-9492-9. Epub 2011 Oct 14.
We report a case of a 40-year-old Caucasian woman who came under our observation with a 7-year history of a chronic erythematous scaly dermatitis, diagnosed as psoriasis, involving gluteal area and thighs, and treated with topical steroids without benefit. During pregnancy, a progressive worsening of her condition and an extension of cutaneous lesions were observed. Her newborn, a 15-day-old girl, presented a similar scaly and squamous lesion on her scalp. Mycological examination was positive for Trichophyton rubrum in both cases, and random amplified polymorphic DNA analysis confirmed the isogenicity of the two isolates. We performed a diagnosis of T. rubrum tinea corporis and tinea capitis. The case we describe illustrates an unusual clinical presentation of tinea corporis with remarkable extension of cutaneous lesions due to the diagnostic delay and the continuous use of local steroids, together with a rare tinea capitis in the newborn. Our experience highlights the possibility of mother-child transmission and the importance of an early diagnosis.
我们报告了一例 40 岁的高加索女性病例，她患有 7 年慢性红斑鳞屑性皮炎，被诊断为银屑病，累及臀部和大腿，外用类固醇治疗无效。怀孕期间，她的病情逐渐恶化，皮肤病变范围扩大。她 15 天大的女婴头皮上也出现了类似的鳞屑和鳞状病变。两种情况下的真菌检查均为红色毛癣菌阳性，随机扩增多态性 DNA 分析证实了两种分离株的同源性。我们诊断为红色毛癣菌体癣和头癣。我们描述的病例说明了体癣的一种不寻常临床表现，由于诊断延迟和持续使用局部类固醇，以及新生儿罕见的头癣，导致皮肤病变显著扩大。我们的经验强调了母婴传播的可能性和早期诊断的重要性。
