Jinling Hospital, Department of Dermatology, Nanjing University, School of Medicine, Nanjing, 210002, People's Republic of China.
Mycopathologia. 2015 Apr;179(3-4):293-7. doi: 10.1007/s11046-014-9834-5. Epub 2014 Dec 7.
A 31-year-old immunocompetent male who presented with a 4-year history of extensive erythematous and scaly plaques involving the abdomen, gluteal and inguen regions with concomitant tinea pedis and onychomycosis is described. Diagnosis was based on positive mycological examination and positive histopathologic examination. Species identification was performed by growth on Sabouraud dextrose agar and by sequencing of the internal transcribed spacer regions of the rDNA region. The pathogen identified was Trichophyton rubrum. The same fungal species was cultured from his abdominal, gluteal, foot and toenail. A combination therapy with systemic terbinafine and topically applied terbinafine cream was successful. A 1-year follow-up did not show any recurrence of infection.
一位 31 岁免疫功能正常的男性,因腹部、臀部和腹股沟区域广泛出现红斑和鳞屑斑块、伴有足癣和甲真菌病而就诊,病史已有 4 年。诊断基于真菌学检查阳性和组织病理学检查阳性。通过在萨布罗琼脂上生长和 rDNA 区内部转录间隔区的测序进行种属鉴定。鉴定出的病原体是红色毛癣菌。从他的腹部、臀部、脚部和脚趾甲中也培养出了相同的真菌。系统应用特比萘芬和局部应用特比萘芬乳膏的联合治疗取得了成功。1 年的随访未显示任何感染复发。