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主观性良性阵发性位置性眩晕。

Subjective benign paroxysmal positional vertigo.

机构信息

ENT Department, Tzanion General Hospital, Piraeus, Greece.

出版信息

Otolaryngol Head Neck Surg. 2012 Jan;146(1):98-103. doi: 10.1177/0194599811425158. Epub 2011 Oct 13.

Abstract

OBJECTIVE

To study the demographic, clinical, pathogenetic, and nystagmographic features and treatment outcomes of subjective benign paroxysmal positional vertigo (BPPV).

STUDY DESIGN

Prospective clinical trial.

SETTING

Tertiary referral center.

SUBJECTS AND METHODS

Sixty-three patients were studied (mean [SD] age 55.4 [9.4] years), 27 men and 36 women, who presented with a positive history for BPPV and Dix-Hallpike or supine roll tests positive for vertigo but negative for nystagmus. A comprehensive history was obtained, followed by clinical examination of the ears, nose, and throat and a complete audiologic and neurotologic examination, including videonystagmography. All patients were treated with the appropriate canalith repositioning procedure, depending on the type of provoking positioning test. A group of 204 patients with typical BPPV were used for comparison.

RESULTS

Forty-five patients with subjective BPPV were successfully treated. Eighteen patients, in most of whom vertigo of other causes was identified, did not respond to treatment. Comparison between patients with subjective and typical BPPV showed similar epidemiological and clinical features. Treatment failed in 13.5% of patients with subjective disease, after excluding patients with different causes of positional vertigo, as compared with 7.8% of patients with typical BPPV (odds ratio = 1.8; 95% confidence interval, 0.7-4.7; P = .32).

CONCLUSION

Subjective BPPV is quite common, accounting for more than one-fourth of patients with typical BPPV and sharing common features with it, with the exception of nystagmus. No statistical difference in treatment outcomes between patients with subjective and typical BPPV was found, but study of a larger sample is needed.

摘要

目的

研究主观性良性阵发性位置性眩晕(BPPV)的人口统计学、临床、发病机制和眼震图特征及治疗效果。

研究设计

前瞻性临床试验。

设置

三级转诊中心。

受试者和方法

63 例患者(平均[标准差]年龄 55.4[9.4]岁,男 27 例,女 36 例),均有 BPPV 阳性病史,Dix-Hallpike 或仰卧位翻滚试验阳性但无眼震的眩晕。详细询问病史,进行耳部、鼻科和咽喉科的临床检查以及全面的听力学和神经耳科学检查,包括视频眼震图。所有患者均根据诱发定位试验的类型接受适当的耳石复位治疗。同时选择了 204 例典型 BPPV 患者作为对照组。

结果

45 例主观性 BPPV 患者成功治疗。18 例患者(多数为其他原因引起的眩晕)对治疗无反应。将主观性和典型 BPPV 患者进行比较,发现两组患者的流行病学和临床特征相似。排除位置性眩晕不同病因的患者后,主观性疾病患者的治疗失败率为 13.5%,而典型 BPPV 患者为 7.8%(比值比=1.8;95%置信区间,0.7-4.7;P=0.32)。

结论

主观性 BPPV 很常见,占典型 BPPV 患者的四分之一以上,与典型 BPPV 有共同的特征,除了眼震。主观性和典型 BPPV 患者的治疗效果无统计学差异,但需要进一步研究大样本。

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