Lee Ju-Hyun, Ko Young-Sun, Shin Hyun-Jong, Yi Joo-Hark, Han Sang-Woong, Kim Ho-Jung
Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.
Electrolyte Blood Press. 2011 Jun;9(1):27-31. doi: 10.5049/EBP.2011.9.1.27. Epub 2011 Jun 30.
This is a case of a sudden cardio-pulmonary arrest in a 29 year-old female, which occurred immediately after a large bolus infusion of propofol (100 mg) intravenously during dilatation and curettage. The arrest suddenly occurred, and the patient was eventually transferred to our emergency room (ER) on cardiopulmonary resuscitation. At that time, severe hyperkalemia up to 9.1 mEq/L and ventricular fibrillation were noted. Resuscitation in ER worked successfully with conversion of electrocardiograph to sinus rhythm, but this patient expired unfortunately. On view of this acute event immediately after the bolus injection of propofol accompanied without other identified causes, severe hyperkalemia induced by propofol was strongly assumed to be the cause of death. To our understanding with the literature survey, propofol as a cause of hyperkalemia has not been well described yet. Through this case, the relationship as a cause and an effect between propofol and hyperkalemia is suggested.
这是一例29岁女性在刮宫术期间静脉快速推注大量丙泊酚（100毫克）后立即发生的心搏骤停病例。心搏骤停突然发生，患者最终在进行心肺复苏的情况下被转送至我们的急诊室。当时，发现严重高钾血症，血钾高达9.1毫当量/升，并伴有心室颤动。在急诊室进行的复苏成功，心电图转为窦性心律，但该患者不幸死亡。鉴于在推注丙泊酚后立即发生这一急性事件且无其他明确病因，强烈推测丙泊酚诱发的严重高钾血症是死亡原因。据我们对文献的研究了解，丙泊酚作为高钾血症的病因尚未得到充分描述。通过该病例，提示了丙泊酚与高钾血症之间的因果关系。
