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脱细胞真皮基质同种异体移植与上皮下结缔组织移植用于牙根覆盖的6个月对比临床研究。

A comparative 6-month clinical study of acellular dermal matrix allograft and subepithelial connective tissue graft for root coverage.

作者信息

Sadat Mansouri S, Ayoubian N, Eslami Manouchehri M

机构信息

Associate Professor, Department of Periodontics, Islamic Azad University, Tehran, Iran.

出版信息

J Dent (Tehran). 2010 Summer;7(3):156-64. Epub 2010 Sep 30.

Abstract

OBJECTIVE

Different surgical procedures have been proposed for the treatment of gingival recessions. The goal of this study was to compare the clinical results of gingival recession treatment using Subepithelial Connective Tissue Graft and an Acellular Dermal Matrix Allograft.

MATERIALS AND METHODS

The present study was performed on 5 patients with 9 bilateral Miller's class I or II gingival recessions. This included 15 premolars and 3 canines. In each patient the teeth were randomly divided in two groups of test (ADMA) and control (SCTG). Clinical parameters including recession height (RH), recession width (RW), keratinized gingiva (KG), clinical attachment level (CAL) and probing depth (PD) were measured at baseline, 2, 4 and 6 months after surgery and data analysis was performed using the Wilcoxon signed rank test.

RESULTS

The mean changes (mm) from baseline to 6 months in SCTG and ADMA were 2.22±0.83 and 1.77±0.66 decrease in RH, 2.55±0.88 and 2.33±0.86 decrease in RW, 1.44±0.88 and 2.0±1.11 increase in KG, 2.33±1.22 and 2.11±0.6 decrease in CAL and finally 0.22±0.66 and 0.33±0.7 decrease in PD, respectively. The differences in mean changes were not significant between the two groups in any of the parameters. The percentage of root coverage was 85.7% and 71.1% for the control and test group, respectively. The changes from baseline to the 6 month visit were significant for both groups in all parameters but PD.

CONCLUSION

Alloderm may be suggested as an acceptable substitute for connective tissue graft considering the root coverage effect and KG width increase.

摘要

目的

已提出不同的外科手术方法用于治疗牙龈退缩。本研究的目的是比较使用上皮下结缔组织移植和脱细胞真皮基质同种异体移植物治疗牙龈退缩的临床效果。

材料与方法

本研究对5例患有9处双侧米勒I类或II类牙龈退缩的患者进行。这包括15颗前磨牙和3颗尖牙。在每位患者中,牙齿被随机分为试验组(ADMA)和对照组(SCTG)两组。在基线、手术后2、4和6个月测量临床参数,包括退缩高度(RH)、退缩宽度(RW)、角化龈(KG)、临床附着水平(CAL)和探诊深度(PD),并使用Wilcoxon符号秩检验进行数据分析。

结果

SCTG组和ADMA组从基线到6个月的平均变化(mm)分别为:RH降低2.22±0.83和1.77±0.66,RW降低2.55±0.88和2.33±0.86,KG增加1.44±0.88和2.0±1.11,CAL降低2.33±1.22和2.11±0.6,最后PD降低0.22±0.66和0.33±0.7。两组在任何参数的平均变化差异均无统计学意义。对照组和试验组的牙根覆盖百分比分别为85.7%和71.1%。两组从基线到6个月复诊时,除PD外的所有参数变化均有统计学意义。

结论

考虑到牙根覆盖效果和KG宽度增加,可将Alloderm建议为结缔组织移植的可接受替代物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7a/3184755/4019388183b5/jod-7-156-g001a.jpg

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