Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-NUS Graduate Medical School (AE), Singapore.
Prehosp Emerg Care. 2012 Apr-Jun;16(2):256-65. doi: 10.3109/10903127.2011.615974. Epub 2011 Oct 14.
The main objective of this study was to establish the spatial variation in ambulance response times for out-of-hospital cardiac arrests (OHCAs) in the city-state of Singapore. The secondary objective involved studying the relationships between various covariates, such as traffic condition and time and day of collapse, and ambulance response times.
The study design was observational and ecological in nature. Data on OHCAs were collected from a nationally representative database for the period October 2001 to October 2004. We used the conditional autoregressive (CAR) model to analyze the data. Within the Bayesian framework of analysis, we used a Weibull regression model that took into account spatial random effects. The regression model was used to study the independent effects of each covariate.
Our results showed that there was spatial heterogeneity in the ambulance response times in Singapore. Generally, areas in the far outskirts (suburbs), such as Boon Lay (in the west) and Sembawang (in the north), fared badly in terms of ambulance response times. This improved when adjusted for key covariates, including distance from the nearest fire station. Ambulance response time was also associated with better traffic conditions, weekend OHCAs, distance from the nearest fire station, and OHCAs occurring during nonpeak driving hours. For instance, the hazard ratio for good ambulance response time was 2.35 (95% credible interval [CI] 1.97-2.81) when traffic conditions were light and 1.72 (95% CI 1.51-1.97) when traffic conditions were moderate, as compared with heavy traffic.
We found a clear spatial gradient for ambulance response times, with far-outlying areas' exhibiting poorer response times. Our study highlights the utility of this novel approach, which may be helpful for planning emergency medical services and public emergency responses.
本研究的主要目的是确定新加坡市院外心脏骤停(OHCA)的救护车反应时间的空间变化。次要目的是研究交通状况以及崩溃时间和日期等各种协变量与救护车反应时间之间的关系。
研究设计为观察性和生态性。从 2001 年 10 月至 2004 年 10 月的全国代表性数据库中收集 OHCA 数据。我们使用条件自回归(CAR)模型来分析数据。在分析的贝叶斯框架内,我们使用了考虑空间随机效应的威布尔回归模型。回归模型用于研究每个协变量的独立影响。
我们的结果表明,新加坡的救护车反应时间存在空间异质性。一般来说,远郊(郊区)地区,如文礼(西部)和三巴旺(北部),救护车反应时间较差。当调整包括距离最近消防站在内的关键协变量时,情况会有所改善。救护车反应时间还与交通状况较好、周末 OHCA、距离最近消防站以及非高峰时段发生的 OHCA 有关。例如,当交通状况较轻时,良好救护车反应时间的危险比为 2.35(95%可信区间[CI]1.97-2.81),而当交通状况中等时,危险比为 1.72(95%CI1.51-1.97)。
我们发现救护车反应时间存在明显的空间梯度,偏远地区的反应时间较差。我们的研究强调了这种新方法的实用性,这可能有助于规划紧急医疗服务和公共应急响应。