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[使用10%水杨酸软膏治疗的银屑病患者血清水杨酸水平]

[Serum levels of salicylic acid in patients with psoriasis treated with 10% salicylic acid ointment].

作者信息

Zgrzybłowski A, Paradecki W, Przybyła L

机构信息

Klinicznego Oddziału Dermatologicznego Wojskowego Szpitala Klinicznego w Bydgoszczy.

出版信息

Przegl Dermatol. 1990 Jan-Feb;77(1):20-4.

PMID:2200078
Abstract

Ten patients with psoriasis were treated for three days with salicylic acid ointment with vaseline vehicle. In all patients the serum concentration of salicylic acid increased systematically and the concentration depended on the amount of ointment used and on psoriasis form. Only in one case of exudative psoriasis the level of salicylic acid reached the value causing intoxication, and produced a diffuse inflammatory erythema with itching. The treatment caused no changes of biochemical indices.

摘要

十名银屑病患者使用凡士林基质的水杨酸软膏治疗三天。所有患者血清水杨酸浓度均系统性升高,且该浓度取决于所用软膏的量及银屑病的类型。仅一例渗出性银屑病患者的水杨酸水平达到中毒值,并出现伴有瘙痒的弥漫性炎性红斑。该治疗未引起生化指标变化。

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