Galy Guillaume, Bauler Stéphanie, Buchi Marjolaine, Pirot Fabrice, Pivot Christine
Groupement hospitalier Édouard-Herriot, Hospices civils de Lyon, Service pharmacie, France.
Bull Cancer. 2011 Oct;98(10):1153-63. doi: 10.1684/bdc.2011.1451.
The interest of centralization of preparations of chemotherapy drugs is in addition to its economic aspect, to secure drugs circuit. The aims of this study are to determine needs in employees and equipments of 11 theoretical levels of production from 1,000 to 50,000 preparations per year and to determine the cost of chemotherapy's preparation for each theoretical unit. The operating cost was divided in four areas of expenditure: employees (66-78%), investment (5-15%), maintenance (3-15%) and consumables (4-16%). If we consider the 11 units, the theoretical cost varies between 27.4 € for a unit with 50,000 preparations per year and 114.1 € for a unit with 1,000 preparations per year. This study shows the importance of setting up an optimal unit of preparations according to its activity and highlights the high cost's variation in relation to the activity of the unit.
化疗药物制剂集中配置的意义不仅在于其经济层面，还在于确保药品流通环节的安全。本研究的目的是确定每年制备1000至50000剂制剂的11个理论生产水平下的人员和设备需求，并确定每个理论单位的化疗制剂成本。运营成本分为四个支出领域：人员（66 - 78%）、投资（5 - 15%）、维护（3 - 15%）和耗材（4 - 16%）。如果考虑这11个单位，理论成本在每年制备50000剂制剂的单位为27.4欧元，到每年制备1000剂制剂的单位为114.1欧元之间变化。本研究表明根据制剂配置单位的活动建立最佳单位的重要性，并突出了成本相对于该单位活动的高度变化。
