Chelsea & Westminster Hospital, London, UK.
Curr Opin Obstet Gynecol. 2011 Dec;23(6):448-53. doi: 10.1097/GCO.0b013e32834cef7a.
Randomized controlled trials and large cohort studies regarding the diagnosis and management of placenta accreta are lacking. This review examines the available evidence.
Avoiding the placenta and leaving it attached at time of elective caesarean section to proceed with either delayed hysterectomy or conservative management is currently recommended. Recent literature has focussed on conservative management. Routine use of methotrexate in conservative management is no longer advocated. Use of emergency balloon catheter placement and embolization in tertiary centres where access to interventional radiology is immediately available may be favourable to prophylactic balloon catheter placement. Follow-up of patients undergoing conservative management should include ultrasonographic follow-up, human chorionic gonadotropin levels have been shown not to correlate with rate of placental resorption.
Women with an antenatal diagnosis of placenta accreta should be managed in a tertiary facility with multidisciplinary input. To determine optimum management strategies, it is imperative that larger studies are carried out in the future. It is essential that the continual monitoring and containment of rising caesarean section rates becomes a priority to prevent a further increase in the incidence of placenta accreta.
随机对照试验和大型队列研究缺乏关于胎盘植入的诊断和管理。本综述检查了现有证据。
目前建议在择期剖宫产时避免胎盘,并将其保留附着,以便随后进行延迟性子宫切除术或保守管理。最近的文献集中于保守管理。在介入放射学可立即获得的三级中心,常规使用氨甲蝶呤进行保守管理不再被提倡。紧急球囊导管放置和栓塞的使用可能优于预防性球囊导管放置。接受保守管理的患者的随访应包括超声随访,人绒毛膜促性腺激素水平已被证明与胎盘吸收的速度无关。
产前诊断为胎盘植入的妇女应在三级医疗机构接受多学科管理。为了确定最佳的管理策略,未来必须进行更大规模的研究。至关重要的是,持续监测和控制剖宫产率的上升应成为优先事项,以防止胎盘植入的发病率进一步增加。