Department of Medicine, Mayo Clinic, Rochester, MN, USA.
J Pain Res. 2011;4:325-9. doi: 10.2147/JPR.S25490. Epub 2011 Oct 7.
Fibromyalgia is a troubling disease characterized by chronic pain. This study explored whether pain and other fibromyalgia symptoms are worse among women who had undergone a hysterectomy with or without an oophorectomy versus those who had not.
Consecutive women who were seen at the Fibromyalgia Treatment Program at a tertiary medical center between 2001 and 2004 and who completed the Fibromyalgia Impact Questionnaire (FIQ) and Short Form-36 Health Survey (SF-36) at initial evaluation were included in this study.
A total of 813 women were included; 328 had had a hysterectomy. Total FIQ scores from women who had had a hysterectomy were higher (worse symptoms) than those who had not (58.1 vs 56.4, P = 0.002). FIQ subscale scores of pain (P = 0.003), fatigue (P = 0.030), stiffness (P = 0.035), and depression (P = 0.008) were also worse in women who had had a hysterectomy. Similar to the FIQ, SF-36 physical component scores were worse in women who had had a hysterectomy (P = 0.045).
Pain and other fibromyalgia symptom severity was worse in women who had had a hysterectomy with or without an oophorectomy.
纤维肌痛是一种以慢性疼痛为特征的棘手疾病。本研究探讨了接受过子宫切除术（伴或不伴卵巢切除术）的女性与未接受过此类手术的女性相比，疼痛和其他纤维肌痛症状是否更严重。
连续选取 2001 年至 2004 年间在三级医疗中心纤维肌痛治疗计划就诊且在初次评估时完成纤维肌痛影响问卷（FIQ）和简明健康调查问卷 36 项（SF-36）的女性患者纳入本研究。
共纳入 813 名女性，其中 328 名接受过子宫切除术。接受过子宫切除术的女性 FIQ 总分（症状更严重）高于未接受过此类手术的女性（58.1 比 56.4，P = 0.002）。FIQ 子量表中疼痛（P = 0.003）、疲劳（P = 0.030）、僵硬（P = 0.035）和抑郁（P = 0.008）的评分在接受过子宫切除术的女性中也更差。与 FIQ 相似，SF-36 生理成分评分在接受过子宫切除术的女性中更差（P = 0.045）。
接受过子宫切除术（伴或不伴卵巢切除术）的女性疼痛和其他纤维肌痛症状严重程度更严重。
