西班牙南部五次旋毛虫病暴发的血清流行病学研究。

Seroepidemiological studies on five outbreaks of trichinellosis in southern Spain.

作者信息

Rodriguez-Osorio M, Gomez-Garcia V, Rodriguez-Perez J, Gomez-Morales M A

机构信息

Department of Immunology, Instituto López-Neyra de Parasitología (C.S.I.C.), Granada, Spain.

出版信息

Ann Trop Med Parasitol. 1990 Apr;84(2):181-4. doi: 10.1080/00034983.1990.11812452.

DOI:10.1080/00034983.1990.11812452

PMID:2200360

Abstract

Five outbreaks of trichinellosis, involving 86 people, took place in Andalucía (Southern Spain) between 1984 and 1987. Four of them were caused by eating infected pork and one by eating wild boar meat. The human sera were analysed by the immunofluorescence assay test, which showed circulating anti-Trichinella antibody titres of up to 1:10240. A micro-ELISA test, carried out with sera from two of the outbreaks, revealed the presence of circulating antigens 68 and 78 days after infection. Finally, 11 of 17 samples of products prepared with pork and wild boar meat showed Trichinella larvae after acid-pepsin digestion. The close geographical localization of three of the outbreaks suggests that the southwestern corner of Spain is an endemic focus of trichinellosis.

摘要

1984年至1987年间，西班牙南部的安达卢西亚发生了5起旋毛虫病疫情，涉及86人。其中4起是由于食用受感染的猪肉引起的，1起是由于食用野猪肉引起的。通过免疫荧光试验对人体血清进行分析，结果显示循环抗旋毛虫抗体效价高达1:10240。对其中两起疫情的血清进行的微量ELISA试验显示，感染后68天和78天存在循环抗原。最后，用猪肉和野猪肉制备的17份产品样本中有11份在经过酸-胃蛋白酶消化后显示出旋毛虫幼虫。其中三起疫情在地理位置上较为接近，这表明西班牙的西南角是旋毛虫病的一个地方性疫源地。