Dombrovskiĭ A M
Antibiot Khimioter. 1990 Apr;35(4):28-32.
Certain pheno- and genotype properties of S. typhimurium and some other representatives of Enterobacteriaceae resistant to antimicrobial drugs were studied. The strains were isolated from children with salmonellosis within 4 months when an infection hospital was subjected to microbiological observation. It was shown that by their antibiotic resistance, phagovars and molecular weights of the plasmid DNas, the strains S. typhimurium were similar to those isolated during hospital infections. The conjugative plasmids responsible for antibiotic resistance in some strains did not differ in their molecular weights and antibiotic resistance markers. The strains S. typhimurium similar in their pheno- and genotype properties were isolated only from 2 patients which allowed one to consider it possible that the patients were infected by the strains of common genesis. Analysis of nonpathogenic representatives of Enterobacteriaceae isolated from the patients along with the S. typhimurium strains confirmed the fact that the patients were infected with the same pathogenic strain.
对鼠伤寒沙门氏菌以及其他一些对抗菌药物耐药的肠杆菌科代表菌的某些表型和基因型特性进行了研究。这些菌株是在一家传染病医院接受微生物学观察的4个月内，从患有沙门氏菌病的儿童中分离出来的。结果表明，就其抗生素耐药性、噬菌体型以及质粒DNA的分子量而言，鼠伤寒沙门氏菌菌株与医院感染期间分离出的菌株相似。一些菌株中负责抗生素耐药性的接合质粒在分子量和抗生素耐药性标记方面并无差异。仅从2例患者中分离出了表型和基因型特性相似的鼠伤寒沙门氏菌菌株，这使得人们认为这两名患者有可能感染了同一来源的菌株。对从患者体内与鼠伤寒沙门氏菌菌株一同分离出的肠杆菌科非致病代表菌的分析证实了患者感染了同一致病菌株这一事实。
