Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA.
Anal Chem. 2011 Dec 1;83(23):9054-9. doi: 10.1021/ac201967m. Epub 2011 Nov 2.
Effective and accurate detection of trace explosives is crucial in the effort to thwart terrorist explosives attacks. A National Institute of Standards and Technology (NIST) standard reference material (SRM) has been developed for the evaluation of trace explosives detectors that sample by collection of residue particles using swiping or air filtration. SRM 2907 Trace Terrorist Explosives Simulants consists of two materials individually simulating the residues of the plastic explosive Semtex [for pentaerytritol tetranitrate (PETN)] and the improvised explosive triacetone triperoxide (TATP). Unique challenges were encountered in the development of these materials, including the selection of suitable inert substrates, material preparation, thermal stability testing, and analytical method development. Two independent analytical methods based on liquid chromatography with ultraviolet absorbance and mass spectrometric detection, LC-UV and LC/MS, respectively, were developed and used to certify the mass fractions of PETN and TATP. These materials were further evaluated for their suitability on a field swipe-sampled trace explosives detectors based on ion mobility spectrometry (IMS).
有效且准确地检测痕量爆炸物对于阻止恐怖分子的爆炸物袭击至关重要。美国国家标准与技术研究院（NIST）已经开发出一种标准参考物质（SRM），用于评估通过使用擦拭或空气过滤收集残留物颗粒进行采样的痕量爆炸物探测器。SRM 2907 痕量恐怖爆炸物模拟物由两种材料组成，分别模拟塑性炸药 Semtex（用于五聚四亚硝胺（PETN））和简易爆炸物三丙酮三过氧化物（TATP）的残留物。在开发这些材料时遇到了独特的挑战，包括选择合适的惰性基质、材料制备、热稳定性测试和分析方法开发。分别基于带有紫外吸收和质谱检测的液相色谱法，开发了两种独立的分析方法，即 LC-UV 和 LC/MS，并用于认证 PETN 和 TATP 的质量分数。这些材料还基于离子迁移谱（IMS）对现场擦拭采样痕量爆炸物探测器的适用性进行了进一步评估。
