Elden Lisa M, Reinders Megan E, Kazahaya Ken, Tom Lawrence W C
Division of Otolaryngology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Int J Pediatr Otorhinolaryngol. 2011 Dec;75(12):1594-8. doi: 10.1016/j.ijporl.2011.09.014. Epub 2011 Oct 17.
To determine the spectrum of diseases and optimal timing of surgical drainage for the opacified sphenoid sinus in children.
Ten year retrospective chart review of children with isolated sphenoid sinus disease.
Fourteen patients (mean age 11 ± 2.8 years, range 6.5-15.1 years) were diagnosed with isolated sphenoid sinus disease. Five patients had acute, severe bacterial sphenoiditis, four had sphenoid mucoceles, three had suspected tumors involving the sphenoid bone, clivus or sella, and two were identified incidentally when imaging studies were obtained for unrelated reasons. Headache was the most common symptom. Cranial nerve or other intracranial complications were present in all of those referred because of infection, but in none of the other patients. Computed tomography (CT) revealed the presence of disease in all cases. Compared with CT, magnetic tomography (MRI) was more helpful in identifying the extent of disease spread in two patients with acute bacterial sphenoiditis and in three patients with suspected tumors. All improved with surgical drainage or biopsy of the suspected tumor. In two cases, children were treated conservatively with antibiotics and the primary symptoms resolved.
Isolated sphenoid sinus disease is rare in children. Those with clinically significant disease presented with progressive, severe headaches and minimal sinus symptoms. MRI studies were important to identify the source of headache and evolving complications in several of these patients.
确定儿童蝶窦混浊的疾病谱及手术引流的最佳时机。
对孤立性蝶窦疾病患儿进行十年回顾性病历审查。
14例患者(平均年龄11±2.8岁,范围6.5 - 15.1岁)被诊断为孤立性蝶窦疾病。5例患有急性重症细菌性蝶窦炎,4例患有蝶窦黏液囊肿,3例怀疑肿瘤累及蝶骨、斜坡或鞍区,2例因无关原因进行影像学检查时偶然发现。头痛是最常见的症状。所有因感染转诊的患者均出现颅神经或其他颅内并发症,但其他患者均未出现。计算机断层扫描(CT)在所有病例中均显示存在疾病。与CT相比,磁共振断层扫描(MRI)在两名急性细菌性蝶窦炎患者和三名疑似肿瘤患者中更有助于确定疾病扩散范围。所有患者经手术引流或疑似肿瘤活检后均有改善。两例患儿采用抗生素保守治疗,主要症状得以缓解。
孤立性蝶窦疾病在儿童中罕见。患有具有临床意义疾病的患儿表现为进行性严重头痛且鼻窦症状轻微。MRI检查对于确定其中一些患者的头痛根源及演变中的并发症很重要。