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免疫功能正常的成人两处罕见部位的多中心性结核。

Multicentric tuberculosis at two rare sites in an immunocompetent adult.

机构信息

Department of Orthopedics, Institute of Medical Sciences, Lanka, Varanasi, 221005, India.

出版信息

J Orthop Traumatol. 2011 Dec;12(4):223-5. doi: 10.1007/s10195-011-0157-8. Epub 2011 Oct 18.

DOI:10.1007/s10195-011-0157-8
PMID:22006175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3225630/
Abstract

The case of a 20-year-old female who presented with refractory coccydynia and sternal pain is described. She was immunocompetent, and had no systemic features. She was diagnosed with tuberculosis of the sternal and coccygeal regions based on magnetic resonance imaging and histopathology of biopsy specimens. Conservative management with oral multidrug antituberculous therapy completely cured the patient, and she had not suffered any recurrence after three years of follow-up. This case highlights the possibility of the multicentric presentation of tuberculosis at two rare sites in the same immunocompetent patient, even though the differential diagnosis was coccydynia.

摘要

本文描述了一例 20 岁女性患者,其表现为难治性尾痛和胸骨痛。患者免疫功能正常,无全身症状。根据磁共振成像和活检标本的组织病理学检查,诊断为胸骨和尾骨区域结核。采用口服多药抗结核治疗的保守治疗方法使患者完全康复,随访 3 年后未再复发。本病例提示,即使鉴别诊断为尾痛,同一免疫功能正常患者也可能在两个罕见部位出现结核的多中心表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ea/4417841/37c3fb8433b4/10195_2011_157_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ea/4417841/5cccdfcf4aee/10195_2011_157_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ea/4417841/37c3fb8433b4/10195_2011_157_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ea/4417841/5cccdfcf4aee/10195_2011_157_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ea/4417841/37c3fb8433b4/10195_2011_157_Fig2_HTML.jpg

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本文引用的文献

1
Isolated tuberculosis of the coccyx.孤立性尾骨结核
J Bone Joint Surg Br. 2006 Oct;88(10):1388-9. doi: 10.1302/0301-620X.88B10.18050.
2
Primary tubercular osteomyelitis of the sternum.胸骨原发性结核性骨髓炎
Indian J Pediatr. 2005 Aug;72(8):709-10. doi: 10.1007/BF02724085.
3
CT and MRI in tuberculous sternal osteomyelitis: a case report.结核性胸骨骨髓炎的CT与MRI表现:1例报告
BMJ Case Rep. 2013 Apr 10;2013:bcr2013008810. doi: 10.1136/bcr-2013-008810.
Clin Imaging. 2002 Mar-Apr;26(2):112-5. doi: 10.1016/s0899-7071(01)00374-6.
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Primary sternal osteomyelitis and septicaemia due to Staphylococcus aureus.
Scand J Infect Dis. 1999;31(1):98-100. doi: 10.1080/00365549950161989.
5
Tuberculosis of the sternum presenting as metastatic disease.表现为转移性疾病的胸骨结核。
Thorax. 1995 Nov;50(11):1223-4. doi: 10.1136/thx.50.11.1223.