Suppr超能文献

术前颈部超声在评估可疑或不确定甲状腺结节患者淋巴结中的作用。

The role of preoperative neck ultrasounds to assess lymph nodes in patients with suspicious or indeterminate thyroid nodules.

机构信息

Endocrine Surgery Section, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

J Surg Oncol. 2012 May;105(6):601-5. doi: 10.1002/jso.22115. Epub 2011 Oct 17.

Abstract

BACKGROUND AND OBJECTIVES

Currently there are no recommendations for obtaining a preoperative neck ultrasound for patients with suspicious or indeterminate thyroid nodules. Because a preoperative surgical ultrasound can detect suspicious lymph nodes that could result in ultimately altering surgical management, we chose to study which variables were predictive of this change.

METHODS

Medical records of 173 patients who presented between January 2006 and December 2010 with suspicious or indeterminate thyroid cytology were retrospectively reviewed. Clinicopathological variables were analyzed to determine factors predictive of malignancy and a change in operative approach.

RESULTS

One hundred thirty-four of 173 patients were evaluable. Seventeen of 134 (12.6%) of the preoperative ultrasounds were suspicious. Seven of 134 (5.2%) patients underwent a formal lymph node dissection based on ultrasound findings. Size of tumor, Bethesda FNAB category, and male gender were associated with malignancy while thyroid nodule microcalcifications and category of FNAB were associated with performing lymph node dissections.

CONCLUSION

Thyroid nodule microcalcifications on ultrasound and category of FNAB appear to be the best predictors of metastatic disease. Because the surgical approach was altered in only a few patients, further analysis is needed to delineate whether performing cervical ultrasound for suspicious/indeterminate nodules is cost effective.

摘要

背景与目的

目前,对于可疑或不确定的甲状腺结节患者,尚无获取术前颈部超声的建议。因为术前手术超声可以检测到可疑的淋巴结,这可能导致最终改变手术管理,因此我们选择研究哪些变量具有预测这种变化的能力。

方法

回顾性分析了 2006 年 1 月至 2010 年 12 月期间因可疑或不确定的甲状腺细胞学而就诊的 173 例患者的病历。分析临床病理变量,以确定恶性肿瘤和手术方式改变的预测因素。

结果

173 例患者中有 134 例可评估。134 例术前超声中,有 17 例(12.6%)为可疑。根据超声检查结果,7 例(5.2%)患者进行了正式的淋巴结清扫术。肿瘤大小、Bethesda FNAB 分类和男性性别与恶性肿瘤相关,而甲状腺结节微钙化和 FNAB 分类与淋巴结清扫术相关。

结论

超声检查的甲状腺结节微钙化和 FNAB 分类似乎是转移性疾病的最佳预测指标。由于只有少数患者的手术方式发生了改变,因此需要进一步分析以确定对可疑/不确定结节进行颈部超声检查是否具有成本效益。

相似文献

7
How to approach thyroid nodules with indeterminate cytology.如何处理细胞学不确定的甲状腺结节。
Ann Surg Oncol. 2010 Aug;17(8):2147-55. doi: 10.1245/s10434-010-0992-5. Epub 2010 Mar 9.

本文引用的文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验