Petric A, Stojanov D, Lilic V, Filipovic S, Bosnjakovic P, Zivadinovic R, Lilic G, Todorovska I, Vrbic S, Pejcic I
Clinic of Obstetrics and Gynecology, Nis Clinical Center, Nis, Serbia.
J BUON. 2011 Jul-Sep;16(3):492-7.
The aim of this paper was to assess the usefulness of the preoperative application of magnetic resonance (MRI) imaging in patients with confirmed endometrial carcinoma.
This prospective study included 50 patients with endometrial cancer. MRI was used for preoperative disease staging and in planning the operative treatment. The parameters monitored by MRI were compared with the findings of curettage pathological examination. Estimated were the depth of myometrial invasion, the involvement of the cervix by the tumor, the presence of adnexal metastases and regional lymph nodes. Sensitivity, specificity, positive (PPV) and negative predictive value (NPV) of the MRI in relation to the aforementioned clinicopathological parameters were assessed.
The presence of myometrial invasion was estimated with 100% specificity, 86% sensitivity, 100% PPV and 40% NPV. The estimation of the depth of myometrial invasion (>or<50%) was defined with 89% sensitivity, 54% specificity, 83% PPV and 60% NPV. MRI provided valuable data about cervical invasion (100% PPV for the presence of cervical invasion and 55% PPV for the depth of cervical invasion), thereby helping to decide on the kind of surgical intervention, the choice of approach (open or laparoscopic surgery) and the choice of the surgeon.
MRI is useful and reliable in preoperative evaluation. The information obtained by MRI provides space and time for planning the treatment modality.
本文旨在评估磁共振成像（MRI）术前应用于确诊子宫内膜癌患者的效用。
这项前瞻性研究纳入了50例子宫内膜癌患者。MRI用于术前疾病分期及手术治疗规划。将MRI监测的参数与刮宫病理检查结果进行比较。评估子宫肌层浸润深度、肿瘤累及宫颈情况、附件转移及区域淋巴结情况。评估MRI对于上述临床病理参数的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。
子宫肌层浸润的评估特异性为100%，敏感性为86%，PPV为100%，NPV为40%。子宫肌层浸润深度（>或<50%）的评估敏感性为89%，特异性为54%，PPV为83%，NPV为60%。MRI提供了有关宫颈浸润的有价值数据（宫颈浸润存在时PPV为100%，宫颈浸润深度时PPV为55%），从而有助于决定手术干预方式、手术入路选择（开放或腹腔镜手术）及术者选择。
MRI在术前评估中有用且可靠。MRI获得的信息为治疗方式规划提供了空间和时间。
