School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China.
Bioinorg Chem Appl. 2011;2011:705989. doi: 10.1155/2011/705989. Epub 2011 Oct 5.
A novel complex of cadmium (II) picrate (pic) with V-shaped ligand bis(N-allylbenzimidazol-2-ylmethyl)benzylamine (babb), with composition Cd(babb)(2)(2), was synthesized and characterized by elemental analyses and electrical conductivity, IR, and UV/visible spectra. The crystal structure of the complex has been determined by the single-crystal X-ray diffraction. In the complex, the coordination sphere around Cd (II) is distorted octahedral, six nitrogen atoms involved in coordination afforded by two tridentate ligand babb. Moreover, The DNA-binding properties of the ligand babb and Cd (II) complex were investigated by spectrophotometric methods and viscosity measurements, and the results suggest that they bind to DNA via an intercalation binding mode, and the Cd (II) complex shows higher affinity than the ligand.
一种新型的镉（II）苦味酸盐（pic）与 V 形配体双（N-烯丙基苯并咪唑-2-基甲基）苄基胺（babb）的配合物，组成[Cd（babb）（2）]（pic）（2），通过元素分析和电导率、IR 和 UV/可见光谱进行了合成和表征。该配合物的晶体结构通过单晶 X 射线衍射确定。在该配合物中，Cd（II）的配位球是扭曲的八面体，六个氮原子通过两个三齿配体 babb 参与配位。此外，通过分光光度法和粘度测量研究了配体 babb 和 Cd（II）配合物的 DNA 结合性质，结果表明它们通过嵌入结合模式与 DNA 结合，并且 Cd（II）配合物比配体具有更高的亲和力。
