Nelius T, Al-Khalil I, Vordermark J, Rinard-Holden K, Cammack T, Mamlok V, Filleur S
Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Lubbock, TX 79415, USA.
Case Rep Med. 2011;2011:432917. doi: 10.1155/2011/432917. Epub 2011 Oct 5.
In the United States, renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancies and 90-95% of all neoplasms arising from the kidney. According to the National Cancer Institute, 58 240 new cases and 13 040 deaths from renal cancer will occur in 2010. RCC usually occurs in older adults between the ages of 50 and 70 and is rare in young adults and children. We describe a case of a TFE3 translocation-associated RCC in a 19-year-old patient presenting as avascular necrosis of the femur. Due to the rarity of this malignancy, we present this case including a review of the existing literature relative to diagnosis and treatment.
在美国，肾细胞癌（RCC）约占成人恶性肿瘤的3%，占所有肾脏肿瘤的90 - 95%。根据美国国立癌症研究所的数据，2010年将有58240例肾癌新发病例和13040例肾癌死亡病例。肾细胞癌通常发生在50至70岁的老年人中，在年轻人和儿童中较为罕见。我们描述了一例19岁患者的TFE3易位相关肾细胞癌，该患者表现为股骨缺血性坏死。由于这种恶性肿瘤较为罕见，我们呈现此病例并对现有的关于诊断和治疗的文献进行综述。
