Department of Pharmacy, University of Patras, GR-26504 Patras, Greece.
Biochemistry. 2011 Nov 15;50(45):9681-3. doi: 10.1021/bi201223u. Epub 2011 Oct 20.
Pentameric ligand-gated ion channels (pLGICs) of the Cys loop family are transmembrane glycoproteins implicated in a variety of biological functions. Here, we present a solution NMR study of the extracellular domain of a prokaryotic pLGIC homologue from the bacterium Gloeobacter violaceus that is found to be a monomer in solution.
五聚体配体门控离子通道（pLGICs）是 Cys 环家族的跨膜糖蛋白，参与多种生物学功能。在这里，我们报道了来自革兰氏阴性菌紫细菌的一种细菌 pLGIC 同源物的胞外结构域的溶液 NMR 研究，结果表明该同源物在溶液中为单体。
