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植物中的菱形蛋白酶——仍处于起步阶段?

Rhomboid proteases in plants - still in square one?

机构信息

The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Rehovot 76100, Israel.

出版信息

Physiol Plant. 2012 May;145(1):41-51. doi: 10.1111/j.1399-3054.2011.01532.x. Epub 2011 Nov 21.

DOI:10.1111/j.1399-3054.2011.01532.x
PMID:22007993
Abstract

Rhomboids are ubiquitous intramembrane serine proteases the sequences of which are found in nearly all sequenced genomes, including those of plants. They were molecularly characterized in a number of organisms, and were found to play a role in a variety of biological functions including signaling, development, apoptosis, mitochondrial integrity, parasite invasion and more. Although rhomboid sequences are found in plants, very little is known about their function. Here, we present the current knowledge in the rhomboids field in general, and in plant rhomboids in particular. In addition, we discuss possible physiological roles of different plant rhomboids.

摘要

菱形蛋白酶是普遍存在的跨膜丝氨酸蛋白酶,其序列几乎存在于所有已测序的基因组中,包括植物基因组。它们在许多生物体中被分子鉴定,并被发现参与各种生物学功能,包括信号转导、发育、细胞凋亡、线粒体完整性、寄生虫入侵等。尽管菱形蛋白酶序列存在于植物中,但对其功能知之甚少。本文综述了菱形蛋白酶领域的现有知识,特别是植物菱形蛋白酶的知识。此外,还讨论了不同植物菱形蛋白酶的可能生理作用。

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