[妊娠滋养细胞肿瘤肺转移的诊治进展]
[Progress of the diagnosis and treatment of pulmonary metastasis of gestational choriocarcinoma].
作者信息
Ma Dongjie, Zhang Zhiyong, Li Shanqing
机构信息
Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2011 Oct;14(10):801-5. doi: 10.3779/j.issn.1009-3419.2011.10.06.
Gestational choriocarcinoma is the most common gestational trophoblastic neoplasia. It is prone to hematogenous metastasis, most commonly to the lungs. With the advent and development of chemotherapy, choriocarcinoma has become a curable tumor. However, patients with drug-resistant and recurrent choriocarcinoma are difficult to treat, even with the management of pulmonary metastasis. Resorting to surgery is also a tough decision given the challenges of identifying the appropriate surgical indication and timing. This review discusses the basic principles of management as well as recent advances in the diagnosis and treatment of patients with pulmonary metastasis of gestational choriocarcinoma.
妊娠性绒毛膜癌是最常见的妊娠滋养细胞肿瘤。它易于发生血行转移，最常见转移至肺部。随着化疗的出现和发展，绒毛膜癌已成为一种可治愈的肿瘤。然而，耐药性和复发性绒毛膜癌患者即使在有肺转移的情况下也难以治疗。鉴于确定合适的手术指征和时机存在挑战，采用手术也是一个艰难的决定。本文综述了妊娠性绒毛膜癌肺转移患者的基本管理原则以及诊断和治疗的最新进展。
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