Vincent Marjolaine, Court-Fortune Isabelle, Karpathiou Georgia, Froudarakis Marios E, Vergnon Jean-Michel
Department of Pneumonology and Thoracic Oncology, University Hospital of Saint-Etienne, Saint-Etienne - France.
Department of Pathology, University Hospital of Saint-Etienne, Saint-Etienne - France.
Tumori. 2017 Nov 15;103(Suppl. 1):e16-e18. doi: 10.5301/tj.5000660.
Gestational choriocarcinomas are highly malignant tumors with elevated serum human chorionic gonadotropin (hCG) levels. We report an extremely rare case of a 27-year-old woman who presented 4 months after normal delivery, with pulmonary, renal and intracardiac metastases of a choriocarcinoma. No primary uterine tumor was found. She was surgically treated for the renal and cardiac metastases as well as with cisplatin-etoposide chemotherapy. No recurrence has been observed 16 years after initial diagnosis, and the patient was able to have a second child. This case report shows that appropriate treatment of metastatic gestational choriocarcinoma can cure the patient without compromising her fertility.
妊娠性绒毛膜癌是血清人绒毛膜促性腺激素(hCG)水平升高的高度恶性肿瘤。我们报告了一例极其罕见的病例,一名27岁女性在正常分娩4个月后出现绒毛膜癌的肺、肾和心脏转移。未发现原发性子宫肿瘤。她接受了肾和心脏转移灶的手术治疗以及顺铂-依托泊苷化疗。初始诊断16年后未观察到复发,患者能够生育第二个孩子。本病例报告表明,对转移性妊娠性绒毛膜癌进行适当治疗可治愈患者且不影响其生育能力。