Takano Yoichi, Maeda Kosaku, Hisamatsu Chieko, Nishijima Eiji
Department of Pediatric Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Pediatr Surg Int. 2012 Jan;28(1):37-41. doi: 10.1007/s00383-011-3006-1.
Slide tracheoplasty for congenital tracheal stenosis was reported by Tsang. This procedure provides good results, but there are few studies about the tracheal growth of post-surgical condition. Recently, not only traditional posterior to anterior slide plasty but also right side to left side slide plasty was reported. We evaluated the tracheal growth after slide tracheoplasty in growing Japanese white rabbit model.
The Japanese white rabbits, weighing 1,600-2,400 g, were used for this study. One-third of the estimated length of the trachea was slantingly resected about an appropriate angle. We performed a slant, side-to-side tracheal anastomosis in two ways (slanted from the front to the back in four animals, and slanted from right to left in four animals) on growing rabbits as an animal model of slide tracheoplasty.
All the rabbits were alive until the 10th week after surgery. There was no evidence of differential growth in any part of the circumference of the normal and anastomotic tracheas. Histologically, all tracheal lumina were completely lined with normal respiratory epithelium and normal surrounding cartilage.
The results presented that these two methods did not prevent the tracheal growth and trachea did not buckle macroscopically. Both slide tracheoplasties did not interrupt the growth of trachea.
曾报道过用于先天性气管狭窄的滑动气管成形术。该手术效果良好，但关于术后气管生长的研究较少。最近，不仅有传统的从前向后滑动成形术，还报道了从右侧向左侧的滑动成形术。我们在生长中的日本白兔模型中评估了滑动气管成形术后的气管生长情况。
本研究使用体重为1600 - 2400克的日本白兔。将气管估计长度的三分之一以适当角度倾斜切除。我们以两种方式对生长中的兔子进行倾斜的侧对侧气管吻合术（4只动物从前向后倾斜，4只动物从右向左倾斜），作为滑动气管成形术的动物模型。
所有兔子在术后第10周均存活。正常气管和吻合口气管圆周的任何部分均无生长差异的证据。组织学上，所有气管腔均完全内衬正常呼吸上皮和正常周围软骨。
结果表明这两种方法均未阻止气管生长，气管在宏观上也未出现扭曲。两种滑动气管成形术均未中断气管生长。
