[帕金森病中黑质纹状体多巴胺能传递的神经心理学]
[The neuropsychology of nigrostriatal dopaminergic transmission in Parkinson's disease].
作者信息
Wallesch C
机构信息
BDH-Klinik Elzach, Am Tannwald 179215 Elzach, Germany.
出版信息
Fortschr Neurol Psychiatr. 2011 Dec;79(12):692-5. doi: 10.1055/s-0031-1281596. Epub 2011 Oct 18.
PMID:22009273
Abstract
Through cortico-subcortico-cortical loop systems, the dopaminergic modulation influences not only motor, but also other executive functions. Neuropsychological findings in Parkinson's disease are reviewed and physiologically interpreted. The theory of a "supervisory attentional system" according to Norman and Shallice (1986) seems to be an adequate model of the interaction of cortex and basal ganglia in executive function and control.
摘要
通过皮质-皮质下-皮质环路系统，多巴胺能调节不仅影响运动功能，还影响其他执行功能。本文回顾了帕金森病的神经心理学发现并进行了生理学解释。诺曼和沙利斯（1986年）提出的“监督注意系统”理论似乎是皮质与基底神经节在执行功能和控制方面相互作用的一个恰当模型。
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