Jeandel P, Chouc P Y, Laroche R
Institut de Médicine Tropicale, Service de Santé des Armées le Pharo Marseille.
Med Trop (Mars). 1990 Apr;50(2):231-5.
Since 1987, some works have been devoted to rheumatological manifestations appearing during the course of the HIV infection. If neurotropism of this retrovirus explains some misleading pseudo radicular aspects of the disease, sometimes revealing, inflammatory neuro-arthropathies are still under discussion. In Tropical Africa, increase of reactive arthritis of REITER's type seems to be correlated with the present epidemic outbreak. It is also admitted that HIV has a direct arthritic effect. These two facts lead to elaborate several pathogenic hypothesis concerning rheumatoid arthritis and spondylarthritis. On the other side, some systemic diseases may appear or be simulated at the occasion of the HIV infection, in particular, some lupoid manifestations. During AIDS, lymphocytic depletion may be at the origin of series of biological abnormalities that have to be known in order to mislead diagnosis.
自1987年以来,一些研究致力于探讨HIV感染过程中出现的风湿性表现。如果这种逆转录病毒的嗜神经性可以解释该疾病一些具有误导性的假根性症状,那么有时会出现的炎症性神经关节病仍在讨论之中。在热带非洲,赖特氏型反应性关节炎的增加似乎与当前的疫情爆发有关。人们也承认HIV具有直接的关节炎作用。这两个事实促使人们提出了一些关于类风湿性关节炎和脊柱关节炎的致病假说。另一方面,在HIV感染时可能会出现或模拟一些全身性疾病,特别是一些狼疮样表现。在艾滋病期间,淋巴细胞耗竭可能是一系列生物学异常的根源,为避免误诊必须了解这些异常。