非功能性胰腺神经内分泌肿瘤的当代治疗管理。
Contemporary management of nonfunctioning pancreatic neuroendocrine tumors.
机构信息
Department of Surgery, University of Michigan, 1500 East Medical Center Drive, SPC 5343, Taubman Center TC 2210D, Ann Arbor, MI 48109-5343, USA.
出版信息
J Gastrointest Surg. 2012 Feb;16(2):435-46. doi: 10.1007/s11605-011-1693-5. Epub 2011 Oct 19.
BACKGROUND
This article reviews the current literature and recommendations pertaining to the management of nonfunctioning pancreatic neuroendocrine tumors.
DISCUSSION
In recent years the detection of nonfunctioning pancreatic neuroendocrine tumors has increased coincident with the increased use of cross-sectional imaging and is now thought to represent 2-10% of all pancreatic tumors. Improved understanding of the biology and behavior of these heterogeneous tumors is needed to guide therapy. The present review discusses diagnostics, therapeutics including emerging molecular analytics, and surveillance recommendations.
背景
本文回顾了有关非功能性胰腺神经内分泌肿瘤管理的现有文献和建议。
讨论
近年来，随着影像学检查的广泛应用，非功能性胰腺神经内分泌肿瘤的检出率有所增加，目前认为其占所有胰腺肿瘤的 2-10%。为了指导治疗，需要更好地了解这些异质性肿瘤的生物学和行为。本综述讨论了诊断、治疗（包括新兴的分子分析）和监测建议。
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