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[喉咽反流病的诊断与治疗]

[Diagnosis and treatment of laryngopharyngeal reflux disease].

作者信息

Zhao Rong, Liu Haibing

机构信息

Department of Otolaryngology, the Central Hospital of Chengdu Railway, Chengdu, 610081, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Aug;25(15):690-1.

PMID:22010339
Abstract

OBJECTIVE

To investigate the diagnosis and treatment of laryngopharyngeal reflux disease.

METHOD

Patients suspect of laryngopharyngeal reflux disease in our out-patient department from Jan 2008 to Jan 2009 were included in this study. All patients were assessed using the reflux symptom index(RSI) and the reflux finding score(RFS). The positive criteria of RSI was score > 13 and that of RFS was score > 7. Fifty-eight double positive patients accepted omeprazole oral administration. After continuous oral administration for three months, all patients received RSI and RFS assessment again.

RESULT

After treatment, the symptoms of 41 patients were significantly alleviated. In addition, RSI were positive in 41 cases and RFS were positive in 37 cases. Thirty-seven cases were double positive.

CONCLUSION

The RSI and RFS could serve as an effective assessment method and could accurately document treatment efficacy in patients with LPR. Proton pump inhibitor such as omeprazole is an effective treatment for patients with LPR.

摘要

目的

探讨喉咽反流病的诊断与治疗。

方法

纳入2008年1月至2009年1月在我院门诊怀疑患有喉咽反流病的患者。所有患者均采用反流症状指数(RSI)和反流发现评分(RFS)进行评估。RSI的阳性标准为评分>13,RFS的阳性标准为评分>7。58例双阳性患者接受奥美拉唑口服治疗。连续口服三个月后,所有患者再次接受RSI和RFS评估。

结果

治疗后,41例患者症状明显缓解。此外,RSI阳性41例,RFS阳性37例。双阳性37例。

结论

RSI和RFS可作为一种有效的评估方法,能准确记录LPR患者的治疗效果。质子泵抑制剂如奥美拉唑是治疗LPR患者的有效药物。

相似文献

1
[Diagnosis and treatment of laryngopharyngeal reflux disease].[喉咽反流病的诊断与治疗]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Aug;25(15):690-1.
2
Reflux symptom index and reflux finding score in otolaryngologic practice.反流症状指数和反流发现评分在耳鼻喉科实践中的应用。
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Influence of age on treatment with proton pump inhibitors in patients with laryngopharyngeal reflux disease: a prospective multicenter study.年龄对喉咽反流病患者质子泵抑制剂治疗的影响:一项前瞻性多中心研究。
JAMA Otolaryngol Head Neck Surg. 2013 Dec;139(12):1291-5. doi: 10.1001/jamaoto.2013.5556.
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[Evaluation of efficacy of esomeprazole treatment in patients with laryngopharyngeal reflux].[埃索美拉唑治疗喉咽反流患者的疗效评估]
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Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Jul;25(13):604-7.
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LPR: how different diagnostic tools shape the outcomes of treatment.喉咽反流:不同诊断工具如何影响治疗结果
J Voice. 2014 May;28(3):362-8. doi: 10.1016/j.jvoice.2013.12.004. Epub 2014 Feb 1.
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Reflux finding score and reflux symptom index as potential predictors for proton pump inhibitor response in globus pharyngeus patients: A prospective study.反流发现评分和反流症状指数作为预测咽喉球部患者质子泵抑制剂反应的潜在指标:一项前瞻性研究。
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Combination of voice therapy and antireflux therapy rapidly recovers voice-related symptoms in laryngopharyngeal reflux patients.嗓音治疗联合抑酸治疗可迅速恢复胃食管反流患者的嗓音相关症状。
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Changes in the quality of life of patients with laryngopharyngeal reflux after treatment.治疗后喉咽反流患者生活质量的变化。
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Laryngopharyngeal reflux: Comparing improvements in reflux symptom index with reflux finding score.喉咽反流:比较反流症状指数与反流性疾病评分的改善情况。
Am J Otolaryngol. 2020 Nov-Dec;41(6):102730. doi: 10.1016/j.amjoto.2020.102730. Epub 2020 Sep 12.

引用本文的文献

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BMC Gastroenterol. 2017 Oct 23;17(1):109. doi: 10.1186/s12876-017-0666-x.