Yang Xue-Jing, Yang Li, Xu Hong, Zhang Mian, Wang Zheng-Tao
Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.
Yao Xue Xue Bao. 2011 Jul;46(7):864-76.
The medicinal herbs derived from genus Senecio have been commonly used in Chinese medicine and triggered attention in recent decades for that they contain the hepatotoxic pyrrolizidine alkaloids. Therefore the botanical pharmacognostic study to authenticate those herbs based on their macroscopic and microscopic characteristics is important for the assurance of safety when they are applied as raw material for extracts or for finished products. In this paper, 13 taxa (11 species and 2 varieties) of Senecio plants were collected and their macroscopic and microscopic characteristics were observed and described by digital microscopic illustration. The results showed that the distribution of collenchyma in the cortex, the level of development for pericycle, the location of the phloem, and the ratio of pith in transverse sections of the stems, and the morphology of the leaf epidermal cells, the stomatal types and the non-glandular hairs in leaf surface view were found to be the main microscopic characteristics for authentication of different Senecio species. The herbs derived from genus Senecio can be distinguished from each other on the basis of their macroscopic and microscopic characteristics, and those observation can be used for the identification of commercial crude drugs from Senecio plants.
千里光属植物来源的草药在中国传统医学中一直被广泛使用,近几十年来因其含有肝毒性吡咯里西啶生物碱而受到关注。因此,基于宏观和微观特征对这些草药进行植物生药学研究,对于确保它们作为提取物原料或成品使用时的安全性至关重要。本文收集了13个千里光属植物类群(11个种和2个变种),并通过数码显微绘图观察和描述了它们的宏观和微观特征。结果表明,皮层中厚角组织的分布、中柱鞘的发育程度、韧皮部的位置、茎横切面中髓的比例,以及叶表皮细胞的形态、气孔类型和叶表面观的非腺毛,是鉴别不同千里光属物种的主要微观特征。千里光属植物来源的草药可以根据其宏观和微观特征相互区分,这些观察结果可用于鉴定千里光属植物的市售药材。