Gomółka Ewa, Gawlikowski Tomasz
Pracownia Toksykologii Analitycznej i Terapii Monitorowanej, Katedra Toksykologii i Chorób Srodowiskowych, Uniwersytet Jagielloński Collegium Medicum w Krakowie.
Przegl Lek. 2011;68(8):413-6.
Carboxyhemoglobin is a specific biomarker of carbon monoxide (CO) exposition. The source of CO indoors are most often gas, oil or carbon furnaces and stoves or bathroom gas heaters. CO intoxication during fire or exposition to car fumes are sporadic. The aim of the study was: to present the frequency of CO intoxications diagnosed in Laboratory of Analytical Toxicology UJ Collegium Medicum in years 2002 - 2010, to present the season trends of CO intoxications, show sex and age structure of CO intoxicated patients. Material were Laboratory of Analytical Toxicology and Drug Monitoring data records from years 2002 - 2010. CO intoxication was confirmed and recognized when COHb blood concentration was higher than 10%. Annual number of CO poisonings was stable in the period of time, varied from 209 to 296 (mean 256,2 CO poisonings per year). Sex structure of CO poisoned patients showed little female dominance (54.6%). Carbon monoxide poisonings distribution was seasonal. The season of intensified CO intoxications lasted from October to March, the highest intensity was in December and January. The CO poisoning problem is still actual. Society education about security, recognition, diagnosis and practice in carbon monoxide exposition is still needful.
碳氧血红蛋白是一氧化碳（CO）暴露的一种特定生物标志物。室内CO的来源最常见的是燃气、燃油或炭火炉以及炉灶或浴室燃气热水器。火灾期间或接触汽车尾气导致的CO中毒较为零星。本研究的目的是：呈现2002年至2010年雅盖隆大学医学院分析毒理学实验室诊断出的CO中毒频率，呈现CO中毒的季节趋势，展示CO中毒患者的性别和年龄结构。材料为2002年至2010年分析毒理学和药物监测实验室的数据记录。当血液中碳氧血红蛋白浓度高于10%时，CO中毒得到确认和认定。在此期间，每年的CO中毒病例数稳定，从209例到296例不等（平均每年256.2例CO中毒）。CO中毒患者的性别结构显示女性略占优势（54.6%）。一氧化碳中毒分布具有季节性。CO中毒加剧的季节从10月持续到3月，强度最高的是12月和1月。CO中毒问题仍然很现实。关于一氧化碳暴露的安全性、识别、诊断及应对措施的社会教育仍然是必要的。
