Felisbino-Mendes Mariana Santos, Géa-Horta Tatiane, Ribeiro Antônio Luiz Pinho, Kac Gilberto, Silqueira Salete Maria de Fátima, Velásquez-Meléndez Gustavo
Nursing School, Universidade Federal de Minas Gerais, Av. Alfredo Balena 190, Belo Horizonte, MG, Brazil.
Arq Bras Endocrinol Metabol. 2011 Aug;55(6):383-8. doi: 10.1590/s0004-27302011000600004.
To investigate associations between metabolic syndrome (MS) and 24-hour blood pressure parameters as a measure of cardiovascular risk (CVR).
136 hypertensive subjects, of both sexes, aged between 29 and 83 years were studied. CVR was defined as having at least three of the following conditions: 1) systolic/diastolic blood pressure (BP) ≥ 140/90 mmHg, absence/attenuation of nighttime fall in BP during sleep, pulse pressure (PP) ≥ 53 mmHg; 2) 24-h PP > 53 mmHg, 3) nighttime PP > 53 mmHg, 4) daytime PP > 53 mmHg and 5) nighttime fall in BP during sleep.
The 24-h PP, daytime PP and nighttime PP were elevated in 54% of the population. Hypertriglyceridemia (52%), low HDL (72.8%), abdominal obesity (60.3%), MS (58.1%), dyslipidemia (88.8%), overweight (74.3%) and obesity (33.8%) were also elevated. Age-adjusted MS was associated with higher CVR (OR = 4.5 and 3.6), 24-h PP (OR = 2.3 and 4.7), and daytime PP (OR = 2.2 and 4.6).
MS was highly prevalent and correlated with altered 24-hour blood pressure parameters.
研究代谢综合征（MS）与作为心血管风险（CVR）指标的24小时血压参数之间的关联。
对136名年龄在29至83岁之间的高血压患者（男女均有）进行了研究。CVR被定义为至少具备以下三种情况：1）收缩压/舒张压（BP）≥140/90 mmHg，睡眠期间血压夜间下降缺失/减弱，脉压（PP）≥53 mmHg；2）24小时PP>53 mmHg；3）夜间PP>53 mmHg；4）白天PP>53 mmHg；5）睡眠期间血压夜间下降。
54%的人群24小时PP、白天PP和夜间PP升高。高甘油三酯血症（52%）、低高密度脂蛋白（72.8%）、腹型肥胖（60.3%）、MS（58.1%）、血脂异常（88.8%）、超重（74.3%）和肥胖（33.8%）也有所升高。年龄调整后的MS与较高的CVR（比值比[OR]=4.5和3.6）、24小时PP（OR=2.3和4.7）以及白天PP（OR=2.2和4.6）相关。
MS非常普遍，且与24小时血压参数改变相关。
