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德国儿科风湿病学会《2010年青少年特发性关节炎基于证据和共识的治疗指南》

[Evidence and consensus based treatment guidelines 2010 for juvenile idiopathic arthritis by the German Society of Paediatric Rheumatology].

作者信息

Dueckers G, Guellac N, Arbogast M, Dannecker G, Foeldvari I, Frosch M, Ganser G, Heiligenhaus A, Horneff G, Illhardt A, Krauspe R, Markus B, Michels H, Schneider M, Singendonk W, Sitter H, Spamer M, Wagner N, Niehues T

机构信息

Zentrum für Kinder- und Jugendmedizin, HELIOS Klinikum Krefeld.

出版信息

Klin Padiatr. 2011 Nov;223(6):386-94. doi: 10.1055/s-0031-1287837. Epub 2011 Oct 19.

Abstract

BACKGROUND

Treatment of Juvenile Idiopathic Arthritis (JIA) has improved quality of life in children and adolescents with JIA. Standardisation of care offers the chance to improve the quality of care of those patients. New studies have been published after completion of our last treatment guideline (2007). An updated consensus process is mandatory.

METHODS

A systematic literature analysis in PUBMED (key words: juvenile idiopathic (rheumatoid) arthritis, therapy; limits: humans, published in the last 3 years, all child 0-18 years, clinical trial) revealed 17 relevant studies. Studies relating to diagnosis of JIA, Uveitis, vaccination, transition were excluded. Representatives nominated by scientific societies and organisations were invited to consensus conferences which were hosted by a professional moderator. The following societies were invited: Berufsverband der Kinder- und Jugendärzte (BVKJ), Deutsche Gesellschaft für Kinder- und Jugendmedizin (DGKJ), Deutsche Gesellschaft für Rheumatologie (DGRh), Deutsche Ophthalmologische Gesellschaft (DOG), Deutsche Rheuma-Liga Bundesverband, Verein zur Förderung und Unterstützung rheumatologisch erkrankter Kinder und deren Eltern, Vereinigung für Kinderorthopädie, Zentraler Verband der Physiotherapeuten und Krankengymnasten (ZVK). Consensus conferences were each attended by more than 95% of the nominated representatives. Consensus statements were confirmed by nominal group technique and Delphi method.

RESULTS AND CONCLUSION

Updated consensus statements regarding drug therapy, symptomatic and surgical management of JIA were compiled and judged strictly by the criteria of Evidence-Based Medicine (EBM).

摘要

背景

幼年特发性关节炎(JIA)的治疗改善了患有JIA的儿童和青少年的生活质量。护理标准化为提高这些患者的护理质量提供了机会。在我们上一版治疗指南(2007年)完成后,新的研究已经发表。必须进行更新的共识制定过程。

方法

在PUBMED上进行系统的文献分析(关键词:幼年特发性(类风湿性)关节炎,治疗;限制条件:人类,过去3年内发表,所有0至18岁儿童,临床试验),共检索到17项相关研究。与JIA诊断、葡萄膜炎、疫苗接种、过渡相关的研究被排除。由科学协会和组织提名的代表受邀参加由专业主持人主持的共识会议。受邀的协会如下:德国儿童和青少年医生职业协会(BVKJ)、德国儿童和青少年医学协会(DGKJ)、德国风湿病学会(DGRh)、德国眼科学会(DOG)、德国风湿病联盟联邦协会、促进和支持患风湿病儿童及其父母协会、儿童矫形外科学会、物理治疗师和运动治疗师中央协会(ZVK)。每次共识会议的出席率均超过95%的被提名代表。通过名义群体技术和德尔菲法确认共识声明。

结果与结论

关于JIA药物治疗、症状治疗和手术治疗的更新共识声明已编制完成,并严格按照循证医学(EBM)标准进行评判。

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