Maine E M, Kimble J
Department of Biology, Syracuse University, NY 13214.
Bioessays. 1990 Jun;12(6):265-71. doi: 10.1002/bies.950120604.
Cell communication is crucial for many aspects of growth and differentiation during the development of the nematode Caenorhabditis elegans. Two genes, glp-1 and lin-12, mediate a number of known cell-cell interactions. Genetic and molecular analyses of these two genes lead to the conclusion that they are structurally and functionally related. We summarize these studies as well as those involving the identification of other genes that interact with glp-1 and/or lin-12.
细胞通讯对于秀丽隐杆线虫发育过程中的生长和分化的许多方面都至关重要。两个基因，glp-1和lin-12，介导了许多已知的细胞间相互作用。对这两个基因的遗传和分子分析得出结论，它们在结构和功能上相关。我们总结了这些研究以及那些涉及鉴定与glp-1和/或lin-12相互作用的其他基因的研究。
