Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Neuroscientist. 2012 Aug;18(4):320-5. doi: 10.1177/1073858411419048. Epub 2011 Oct 19.
In contrast to a long-held view that structural brain plasticity is restricted to critical periods during ontogenesis, it is now well established that the adult human brain preserves its capacity for functional and structural changes throughout life. Although early experimental studies were mainly performed in animals, technical developments especially in the field of MRI enabled the non-invasive observation of functional and structural reorganization in the human brain. This article reports recent insights in human brain plasticity with particular emphasis on (dynamic) learning-related structural gray and white matter changes and its behavioral correlates.
与长期以来认为结构性大脑可塑性仅限于个体发生期间的关键期的观点相反，现在已经明确，成年人的大脑在整个生命过程中都保持其功能和结构变化的能力。尽管早期的实验研究主要在动物中进行，但技术的发展，特别是在 MRI 领域的发展，使得可以在不进行侵入性操作的情况下观察人类大脑的功能和结构重组。本文报告了人类大脑可塑性的最新研究结果，特别强调了（动态）与学习相关的结构灰质和白质变化及其行为相关性。
