Division of Vector Biology and Phytochemistry, Department of Zoology, Annamalai University, Annamalainagar, India.
Eur Rev Med Pharmacol Sci. 2011 Sep;15(9):1010-9.
To determine the larvicidal and repellent activities of Coccinia (C) indica Wight and Arnold (Family:Cucurbitaceae) extract against Culex (Cx.) quinquefasciatus, Aedes (Ae.) aegypti and Anopheles (An.) stephensi.
The ovicidal activity was determined against three mosquito species to various concentrations ranging from 50-300 ppm under the laboratory conditions. The hatch rates were assessed 48 h post treatment. The repellent efficacy was determined against three mosquito species at three concentrations viz., 1.0, 2.5 and 5.0 mg/cm2 under the laboratory conditions.
Among five solvent extracts tested, the methanol extract have most promising ovicidal activity. The methanol extract exerted zero hatchability (100% mortality) at 150 ppm for Cx. quinquefasciatus, at 200 ppm for Ae. aegypti and An. stephensi. The methanol extract of C. indica found to be more repellency than the other extracts. A higher concentration of 5.0 mg/cm2 provided 100% protection up to 270 min against Cx. quinquefasciatus and 210 min against Ae. aegypti and An. stephensi, respectively. The results clearly show that repellent activity was dose dependent.
From the results it can be concluded the crude extract of C. indica was an excellent potential for controlling Cx. quinquefasciatus, Ae. aegypti and An. stephensi mosquitoes.
确定苦葫芦（C） indica Wight 和 Arnold（葫芦科）提取物对致倦库蚊、埃及伊蚊和按蚊的杀幼虫和驱避活性。
在实验室条件下，将杀卵活性测定为针对三种蚊虫的不同浓度范围从 50-300ppm。处理后 48 小时评估孵化率。在实验室条件下，以三个浓度（1.0、2.5 和 5.0mg/cm2），针对三种蚊虫确定驱避效力。
在所测试的五种溶剂提取物中，甲醇提取物具有最有前途的杀卵活性。甲醇提取物在 150ppm 时对致倦库蚊、在 200ppm 时对埃及伊蚊和按蚊表现出零孵化率（100%死亡率）。苦葫芦的甲醇提取物比其他提取物具有更高的驱避性。较高浓度的 5.0mg/cm2 对致倦库蚊提供了 100%的保护，长达 270 分钟，对埃及伊蚊和按蚊分别为 210 分钟。结果清楚地表明，驱避活性是剂量依赖性的。
从结果可以得出结论，苦葫芦的粗提取物是控制致倦库蚊、埃及伊蚊和按蚊的潜在优秀选择。
