Woods Adam J, Mennemeier Mark, Garcia-Rill Edgar, Huitt Tiffany, Chelette Kenneth C, McCullough Gary, Munn Tiffany, Brown Ginger, Kiser Thomas S
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Neurocase. 2012;18(2):115-22. doi: 10.1080/13554794.2011.568498. Epub 2011 Oct 21.
The relationship between arousal, perception, and visual neglect was examined in this case study. Cold pressor stimulation (CPS: immersing the foot in iced water) was used to manipulate arousal and to determine its effects on contralesional neglect, perception of stimulus intensity (magnitude estimation), reaction time, and an electrophysiological correlate of ascending reticular activating system activity (i.e., the P50 potential). Measures that normalized from baseline following CPS included contralesional neglect on a clock drawing test, perception of stimulus magnitude, and P50 amplitude. The P50 amplitude returned to its abnormally low baseline level 20 min after CPS ended, indicating that CPS increased arousal.
在本案例研究中,对觉醒、知觉和视觉忽视之间的关系进行了研究。采用冷加压刺激(CPS:将脚浸入冰水中)来控制觉醒,并确定其对患侧忽视、刺激强度感知(数量估计)、反应时间以及网状上升激活系统活动的电生理相关指标(即P50电位)的影响。CPS后从基线恢复正常的指标包括时钟绘图测试中的患侧忽视、刺激大小感知和P50波幅。CPS结束20分钟后,P50波幅恢复到异常低的基线水平,表明CPS增加了觉醒。