Department of Periodontics, Case Western Reserve University School of Dental Medicine, 2124 Cornell Road, Cleveland, OH 44106, USA.
J Periodontol. 2012 Jun;83(6):684-9. doi: 10.1902/jop.2011.110230. Epub 2011 Oct 20.
Periodontitis and obesity are both chronic health problems, and the literature supports an association between the two. Weight loss after bariatric surgery (BS) has been shown to decrease overall mortality as well as the development of new health-related conditions in morbidly obese patients. The present study aims to assess whether significant weight loss would improve the response to non-surgical periodontal therapy in obese patients.
This study included 30 obese (body mass index >30 kg/m(2)) patients affected with chronic periodontitis. Of these, 15 patients had previously undergone BS and lost ≥40% of their excess weight for ≥6 months after surgery. The other 15 patients were also obese but did not have the surgery, nor did they lose weight to serve as a control group. All participants received non-surgical periodontal therapy (scaling and root planing and oral hygiene instructions). Probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI), and plaque index were measured at baseline and at 4 to 6 weeks after the periodontal treatment. Descriptive statistics, linear mixed-effects models, and linear regression models were used for data analysis.
The mean age of the study participants was 47.1 ± 11.5 years, and 36.7% of the participants were males. There was a statistically significant improvement after periodontal therapy in the BS compared with the obese group (P <0.05). The PD had a mean reduction of 0.45 mm in the BS group versus 0.28 mm in the control group. The reduction in CAL was 0.44 mm versus 0.30 mm, percentage of BOP sites was 16% versus 15%, and GI was 1.03 versus 0.52 in the BS and control groups, respectively.
An improved response to non-surgical periodontal therapy is observed in obese patients who had significant weight loss after BS compared with obese patients who did not have such a surgery.
牙周炎和肥胖都是慢性健康问题，文献支持两者之间存在关联。减重手术（BS）后的体重减轻已被证明可降低肥胖患者的总体死亡率和新发生的与健康相关的疾病的发病率。本研究旨在评估显著的体重减轻是否会改善肥胖患者对非手术牙周治疗的反应。
本研究纳入了 30 名患有慢性牙周炎的肥胖（体重指数>30kg/m2）患者。其中，15 名患者之前接受过 BS，并在手术后 6 个月内体重减轻了≥40%的超重体重。其余 15 名患者也肥胖，但未进行手术，也未减轻体重作为对照组。所有参与者均接受非手术牙周治疗（洁治和根面平整及口腔卫生指导）。在基线和牙周治疗后 4 至 6 周时测量探诊深度（PD）、临床附着水平（CAL）、探诊出血（BOP）、牙龈指数（GI）和菌斑指数。采用描述性统计、线性混合效应模型和线性回归模型进行数据分析。
研究参与者的平均年龄为 47.1±11.5 岁，36.7%为男性。BS 组与肥胖组相比，牙周治疗后有统计学意义的改善（P<0.05）。BS 组 PD 的平均减少量为 0.45mm，对照组为 0.28mm。CAL 的减少量为 0.44mm，对照组为 0.30mm，BOP 位点的百分比为 16%，对照组为 15%，GI 为 1.03，对照组为 0.52。
与未接受此类手术的肥胖患者相比，BS 后体重显著减轻的肥胖患者对非手术牙周治疗的反应得到改善。
