Fleury A A
Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia.
Compendium. 1990 Apr;11(4):210, 212, 214 passim.
The attainment of clinically acceptable local anesthesia is often problematic in the treatment of symptomatic pulpitis and symptomatic apical periodontitis. This article reviews the literature to identify the extent of this problem and to understand the organic components involved with this condition. Inflammation, infection, pH changes, alteration in nerve cell membranes, and anatomic variations are all possible causes for failure of local anesthesia during emergency endodontic therapy.
在有症状的牙髓炎和有症状的根尖周炎治疗中，实现临床上可接受的局部麻醉往往存在问题。本文回顾文献，以确定该问题的严重程度，并了解与该病症相关的有机组成部分。炎症、感染、pH值变化、神经细胞膜改变以及解剖变异都是急诊牙髓治疗期间局部麻醉失败的可能原因。
